Spermidine from wheat and aged cheese may boost vaccine response in older adults
Spermidine, a naturally occurring compound found in wheat germ, mushrooms, and aged cheese, may help adults over 65 mount stronger immune responses after vaccination. In a small pilot trial, participants received spermidine supplements following their third COVID-19 vaccine dose. The greatest benefits — higher antibody levels and stronger activity against multiple variants — appeared in those who had initially responded poorly to vaccination.
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