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Migraines explained: causes, triggers and modern treatments

Migraines affect women far more than men and were misunderstood for centuries, from ancient Egyptian remedies to 20th-century theories blaming repressed emotions. The discovery of the neuropeptide CGRP as a key driver led to a new class of treatments — anti-CGRP monoclonal antibodies approved around 2018 — marking the biggest therapeutic advance in decades. Triggers vary greatly between individuals and include hormonal changes, stress, poor sleep and certain foods.

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