Serotonin may speed heart valve disease in SSRI users with specific gene variant
Columbia University scientists have found that serotonin may accelerate the progression of degenerative mitral regurgitation, a common heart valve disease. Patients who take SSRI antidepressants and carry a specific genetic variant appear to develop severe valve damage sooner, potentially needing surgery at a younger age. The finding opens new questions about SSRI use in at-risk cardiac patients.
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