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Good morning, and welcome to a new week from STAT’s London outpost, with Andrew Joseph here filling in for Mr. Pharmalot. This country is celebrating its World Cup win last night (or rather, very early this morning local time — lots of bleary-eyed people out in the neighborhood today), and I can only hope that the U.S. will be in the same place tomorrow. Yet the World Cup (and Wimbledon) can’t completely distract from the news of the day, so onto the headlines we go. …

Novartis is pushing deeper into antibody-drug conjugate development, paying $1.1 billion upfront to buy Myricx Bio for a pipeline based on a novel payload , Fierce Biotech writes. The Swiss pharma company has been slower to buy into ADCs than some of its peers, but it’s made its move with London-based Myricx, which is designing cancer treatments that deliver N-myristoyltransferase inhibitor (NMTi) payloads. It’s a bit of a different approach from other ADCs, which Novartis predicts could tackle resistance and other limitations of existing payloads, broadening the use of ADCs across multiple tumor types.

While clinical trials got caught up in the Trump administration’s attack on policies related to diversity, equity, and inclusion, congressional Republicans would like to change that , STAT says. Last month, the Republican-controlled House passed a bill, mostly along party lines, to fund the Food and Drug Administration that was accompanied by a report that, while not legally binding, tells agency officials what congressional appropriators expected of them. The report states that it wants the FDA to continue implementing a law that requires companies to give the FDA their plans for diversifying clinical trials.

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Pasadena, California — NASA's new alien-hunting telescope, the Habitable Worlds Observatory (HWO), will be serviceable out in space (and it will have gamma-ray detectors, to boot).

Do you remember seeing NASA's Space Shuttle astronauts working on the Hubble Space Telescope out in space? Well, it will likely be robots this time around, but NASA is planning for HWO to be serviceable, which means that they will need to figure out a way to work on, repair, and maintain the observatory while it operates roughly a million miles (1.5 million kilometers) away.

"HWO will have to be serviceable to some extent," NASA's astrophysics division director Shawn Domagal-Goldman told Space.com during a session at the American Astronomical Society's (AAS) 248th meeting in Pasadena, California.

From Hubble to HWO

The Habitable Worlds Observatory (HWO) is NASA's next planned flagship space telescope. But what separates it from previous space telescopes like Hubble or the James Webb Space Telescope (JWST) is its purpose: to look for and study rocky, Earth-like planets orbiting sun-like stars. In other words, to find planets that could hold life. The mission won't just hunt for aliens, but rather explore these habitable planets and their atmospheres, expanding our understanding of other worlds while also being used for a variety of astronomical purposes. And by making it serviceable, NASA will not just extend HWO's life, but it will also open the door for future technologies that can be used to enhance the observatory.

Hubble was a unique case. As the space telescope came about at roughly the same time as NASA's Space Shuttle program, and the telescope was designed to function in low-Earth orbit, it was a natural fit that astronauts go out to assemble, repair and maintain the observatory. "There were decisions made early on that the avionics would be modular in a way that astronauts could take the computer out and put a new computer in, or take a gyroscope out and put a new gyroscope in," former NASA astronaut and former NASA Chief Scientist John Grunsfeld, who today works independently as a consultant in the space industry, told Space.com.

However, HWO won't be so close to us. Instead, it will be located nearby L2, or the Sun-Earth Lagrange point 2, a point out in space roughly one million miles (1.5 million kilometers) away where the gravitational pull of the sun and Earth combine to keep objects in the same orbital period as Earth. This position, which is also home for the JWST, allows space telescopes to stay in sync with Earth, making communication easier. It also makes an astronaut mission quite difficult, if not nearly impossible with the technology we have today.

While the JWST was sent out to this distant vantage point without plans for servicing the telescope, HWO will "have to" be serviceable, according to Domagal-Goldman and further confirmed with NASA's press office. Servicing the observatory could look like anything from instrument swaps to regular maintenance or as-needed repairs, but it could also entail assembling the observatory itself. "If the telescope is too large to launch [fully assembled]," Domagal-Goldman added, it might need to be "assembled in space."

When the JWST went to L2, the mission team realized the problem with micrometeorites was a bit bigger than they anticipated. "We've learned that there's more micrometeorites and they're larger than we expected," said Grunsfeld, "and so you might be able to want to put a patch over a sunshield or a patch on a barrel to patch a hole — and, in principle, robotics could do that."

NASA has yet to confirm details about exactly how they plan to service the new observatory, which makes sense as the design of HWO itself is still in flux. But with L2 being so far away, it's logical to assume that it will need to be supported robotically, instead of with astronauts working out in space like with Hubble. We don't know what these future space telescope robot mechanics might look like, but they will have to be very capable to work on such a powerful observatory all the way out at L2.

"This will be by far the most challenging observatory that we've ever built," Grunsfeld said. "It's just remarkable that we are so bold as to think we can do it, and to be really close to showing that we can … so since we're just getting started, this is the time to have the discussion about should it be serviceable or not."

NASA's Goddard Space Flight Center Conceptual Image Lab NASA's Goddard Space Flight Center Conceptual Image Lab NASA Science is the driving force

In addition to extending HWO's longevity by building it in a way that will allow it to be repaired out in space, making the observatory serviceable will also stretch its science capabilities in ways we can't yet imagine. If we look at Hubble's history, its instruments have been swapped out for newer, better versions over time that have not just allowed the telescope to continue functioning, it has allowed the telescope to evolve with changing technologies. From Hubble's gyroscopes to the Wide-Field Camera 3 swapped out in 2009, the telescope has benefitted from many technological upgrades. With servicing capabilities, the same could be true for HWO.

HWO is still fairly early in its development, and many years from launch (estimated for the 2040s). But NASA is laying the groundwork for this mission with the upcoming flagship mission the Nancy Grace Roman Space Telescope. This mission carries with it a technology demonstration called the Roman Coronagraph Instrument. Essentially an "exoplanet camera," this instrument will block the glare of far-off stars, getting a direct look at the planets in their orbit. Roman will provide a proving ground for this next-gen coronagraph technology. But even if HWO launches with an advanced version of this coronagraph five , 10 or even 15 years following launch there could be even better planet-spotting technology available.

"I'm sure we will be highly motivated if we see a little rocky planet around a nearby star that kind of looks like Earth," Grunsfeld said, "we're going to be highly motivated to send a higher resolution spectrograph, or some different type of detector … up there as fast as we can. So that's the primary driver of servicing, is to be able to put in new scientific instruments."

By making HWO serviceable, NASA will enable the use of future technologies without having to launch entirely new space telescopes to support them. This is a cost-effective method, but it might also enable the deployment of future technologies that might otherwise not have a place to operate out in space.

"Imagine 20 years from now, or 25 years from now, that there'll be a robust space industry doing servicing, such that we could have a commercial servicer deliver new scientific instruments to habitable worlds," Grunsfeld said. They would simply "slide the old ones out, [and slide] the new ones in."

Speaking of future technologies, this decision to make HWO serviceable wasn't all that NASA revealed at AAS. Domagal-Goldman also shared that HWO will be equipped with Gamma-ray detectors. The specific details of these detectors and what they will be used for is also to-be-determined, but with HWO being serviceable, these detectors could continue to evolve with the observatory over time, enabling future astronomy that we can't even imagine today.